Metabolic modeling for cell factory engineering

4. Analyzing metabolic models

Overview

Teaching: 30 min
Exercises: 30 min
Questions
  • How uniquely determined is the flux distribution returned by flux balance analysis?

  • What is the optimal oxygen uptake rate at maximum growth?

Objectives
  • Learn how to determine flux capacities using flux variability analysis.

  • Learn how to generate phenotypic phase planes for different fluxes.

Key Points