NADP⁺

9 Malonyl-CoA + 11 NADPH + 10 H⁺ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO₂ + 11 NADP⁺ + S-Adenosyl-L-homocysteine + 6 H₂O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H⁺: h_c, Acyl-carrier protein: ACP_c

2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H⁺ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO₂ + 2 NADP⁺ + S-Adenosyl-L-homocysteine + H₂O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H⁺: h_c

L-Glutamine + 2-Oxoglutarate + NADPH + H⁺ ⇄ 2 L-Glutamate + NADP⁺ (1.4.1.13)
2-Oxoglutarate: akg_c, L-Glutamine: gln__L_c, NADPH: nadph_c, H⁺: h_c

2-Oxoglutarate + Ammonia + NADPH + H⁺ ⇄ L-Glutamate + NADP⁺ + H₂O (1.4.1.13)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H⁺: h_c

2-Oxoglutarate + Ammonia + NADPH + H⁺ ⇄ L-Glutamate + NADP⁺ + H₂O (1.4.1.4)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H⁺: h_c