CO2

Overview of the growth coupled pathways towards this compound.

Available chemistries

Reaction routes

CO2mth1

2 S-Adenosyl-L-methionine + Precorrin 6Y ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2 (2.1.1.132)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

Precorrin 6Y

Precorrin 6X + NADPH + H+ ⇄ Precorrin 6Y + NADP+ (1.3.1.54)
NADPH: nadph_c, H+: h_c

Reversibility:
?

Precorrin 6X

Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c

Reversibility:
?

Precorrin 5

S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

Precorrin 4

S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

Precorrin 3B

Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c

Reversibility:
?

Precorrin 3A

S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c

Reversibility:
?

CO2mth1

9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c

Reversibility:
?

CO2mth1

2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c

Reversibility:
?

CO2mth5

Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c

Reversibility:
?

CO2mth5

Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

Fe-coproporphyrin III

Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c

Reversibility:
?

Fe-coproporphyrin III

Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c

Reversibility:
?

Harderoheme III

Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c

Reversibility:
?