Available chemistries
amn1
R + glu__L_c → R-aminated + akg_c
amn3
R + ala__L_c → R-aminated3 + pyr_c
amn4
R + gly_c → R-aminated4 + glx_c
mth5
R + amet_c → met__L_c + dad_5_c + R-methylated5
Reaction routes
- Ammoniamth5
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_cReversibility:?- 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_cReversibility:?
- Ammoniaamn1
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_cReversibility:2.63±0.06
- Ammoniaamn1
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_cReversibility:2.63±0.04
- Ammoniaamn1
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_cReversibility:2.63±0.04
- Ammoniaamn1
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_cReversibility:2.63±0.06
- Ammoniaamn1
L-Glutamate + O2 + H2O ⇄ 2-Oxoglutarate + Ammonia + Hydrogen peroxide (1.4.3.11)
L-Glutamate: glu__L_c, O2: o2_c, H2O: h2o_cReversibility:-18.26±0.68
- Ammoniaamn1
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_cReversibility:-5.05±0.25
- Ammoniaamn3
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_cReversibility:2.66±0.09