Available chemistries
amn1
R + glu__L_c → R-aminated + akg_c
amn3
R + ala__L_c → R-aminated3 + pyr_c
amn4
R + gly_c → R-aminated4 + glx_c
hdg3
R + lac__D_c → R-H2 + pyr_c
hdg4
R + trdrd_c → R-H2 + trdox_c
mth1
R + amet_c → R-methylated + ahcys_c
Reaction routes
- H+hdg3
(R)-Lactate + NAD+ ⇄ Pyruvate + NADH + H+ (1.1.1.28)
(R)-Lactate: lac__D_c, NAD+: nad_cReversibility:4.16±0.42
- H+hdg4
Thioredoxin + NADP+ ⇄ Thioredoxin disulfide + NADPH + H+ (1.8.1.9)
Thioredoxin: trdrd_c, NADP+: nadp_cReversibility:1.56±0.30
- H+mth1
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_cReversibility:?
- H+mth1
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine ⇄ dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ (2.1.1.235)
S-Adenosyl-L-methionine: amet_cReversibility:?- dTDP-3-amino-3,6-dideoxy-D-glucose
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_cReversibility:6.60±0.49- 3,6-Dideoxy-3-oxo-dTDP-D-glucose
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_cReversibility:-6.21±0.77
- H+amn1
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_cReversibility:6.43±0.13
- H+amn1
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_cReversibility:2.63±0.06
- H+amn1
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_cReversibility:6.43±0.12
- H+amn1
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_cReversibility:2.63±0.04
- H+amn1
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_cReversibility:2.63±0.04
- H+amn1
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_cReversibility:2.63±0.06