H+

Overview of the growth coupled pathways towards this compound.

Available chemistries

Reaction routes

H+hdg3

(R)-Lactate + NAD+ ⇄ Pyruvate + NADH + H+ (1.1.1.28)
(R)-Lactate: lac__D_c, NAD+: nad_c

Reversibility:
4.16±0.42

H+hdg4

Thioredoxin + NADP+ ⇄ Thioredoxin disulfide + NADPH + H+ (1.8.1.9)
Thioredoxin: trdrd_c, NADP+: nadp_c

Reversibility:
1.56±0.30

H+mth1

S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c

Reversibility:
?

H+mth1

dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine ⇄ dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ (2.1.1.235)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

dTDP-3-amino-3,6-dideoxy-D-glucose

3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c

Reversibility:
6.60±0.49

3,6-Dideoxy-3-oxo-dTDP-D-glucose

dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c

Reversibility:
-6.21±0.77

H+amn1

2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c

Reversibility:
6.43±0.13

H+amn1

L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c

Reversibility:
2.63±0.06

H+amn1

2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c

Reversibility:
6.43±0.12

H+amn1

L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c

Reversibility:
2.63±0.04

H+amn1

L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c

Reversibility:
2.63±0.04

H+amn1

L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c

Reversibility:
2.63±0.06

H+amn3

L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c

Reversibility:
2.66±0.09

H+amn4

Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c

Reversibility:
4.01±0.26