Available chemistries
amn1_rev
R-aminated + akg_c → R + glu__L_c
Transaminase
amn4_rev
R-aminated4 + glx_c → R + gly_c
Transaminase
Reaction routes
- 4-Hydroxy-2-quinolinecarboxylic acidamn1_rev
L-Kynurenine + 2-Oxoglutarate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O (2.6.1.7)
2-Oxoglutarate: akg_cReversibility:-24.39±1.13- L-Kynurenine
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_cReversibility:-14.33±1.51- L-Formylkynurenine
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_cReversibility:-87.40±1.77
- 4-Hydroxy-2-quinolinecarboxylic acidamn4_rev
L-Kynurenine + Glyoxylate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_cReversibility:-26.11±1.17- L-Kynurenine
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_cReversibility:-14.33±1.51- L-Formylkynurenine
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_cReversibility:-87.40±1.77