alpha-Tocopherol

S-Adenosyl-L-methionine + gamma-Tocopherol ⇄ S-Adenosyl-L-homocysteine + alpha-Tocopherol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c

gamma-Tocopherol

2,3-Dimethyl-5-phytylquinol ⇄ gamma-Tocopherol (5.5.1.24)

Reversibility:

-25.65±2.38

2,3-Dimethyl-5-phytylquinol

2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine ⇄ 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine (2.1.1.295)
S-Adenosyl-L-methionine: amet_c

Reversibility:

?

2-Methyl-6-phytylquinol

Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO₂ (2.5.1.115)

Reversibility:

-18.74±0.67

Phytyl diphosphate

Geranylgeranyl diphosphate + 3 H⁺ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP⁺ (1.3.1.83)
H⁺: h_c, NADPH: nadph_c

Reversibility:

-16.03±0.55

Geranylgeranyl diphosphate

trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c

Reversibility:

-16.40±0.59

Homogentisate

4-Maleylacetoacetate ⇄ Homogentisate + O₂ (1.13.11.5)

Reversibility:

66.40±1.53

4-Maleylacetoacetate

4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)

Reversibility:

0.00±0.00

4-Fumarylacetoacetate

Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H₂O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c

Reversibility:

25.11±1.03