3-Hydroxy-4-methylanthranilate

S-Adenosyl-L-methionine + 3-Hydroxyanthranilate ⇄ S-Adenosyl-L-homocysteine + 3-Hydroxy-4-methylanthranilate (2.1.1.97)
S-Adenosyl-L-methionine: amet_c

3-Hydroxyanthranilate

2-Amino-3-carboxymuconate semialdehyde ⇄ 3-Hydroxyanthranilate + O₂ (1.13.11.6)

Reversibility:

62.05±1.72

2-Amino-3-carboxymuconate semialdehyde

2-Aminomuconate semialdehyde + CO₂ ⇄ 2-Amino-3-carboxymuconate semialdehyde (4.1.1.45)
CO₂: co2_c

Reversibility:

8.58±0.89

2-Aminomuconate semialdehyde

2-Aminomuconate + H⁺ + NADH ⇄ 2-Aminomuconate semialdehyde + NAD⁺ + H₂O (1.2.1.32)
H⁺: h_c, NADH: nadh_c

Reversibility:

8.80±0.22

2-Aminomuconate

gamma-Oxalocrotonate + Ammonia ⇄ 2-Aminomuconate + H₂O (3.5.99.5)
Ammonia: nh4_c

Reversibility:

12.16±0.62

gamma-Oxalocrotonate

2-Hydroxy-2,4-pentadienoate + CO₂ ⇄ gamma-Oxalocrotonate (4.1.1.77)
CO₂: co2_c

Reversibility:

8.07±0.84

2-Hydroxy-2,4-pentadienoate

2-Hydroxy-6-ketononatrienedioate + H₂O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H₂O: h2o_c

Reversibility:

-19.04±0.77

2-Hydroxy-2,4-pentadienoate

2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H₂O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H₂O: h2o_c

Reversibility:

-19.56±0.69