2'-O-Methylisoliquiritigenin

Overview of the growth coupled pathways towards this compound.

Available chemistries

Reaction routes

2'-O-Methylisoliquiritigeninmth1

S-Adenosyl-L-methionine + Isoliquiritigenin ⇄ S-Adenosyl-L-homocysteine + 2'-O-Methylisoliquiritigenin (2.1.1.154)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

Isoliquiritigenin

p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ ⇄ Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O (2.3.1.170)
Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c

Reversibility:
-10.48±0.66

p-Coumaroyl-CoA

ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c

Reversibility:
-1.87±0.20

4-Coumarate

L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c

Reversibility:
-15.32±1.19