3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene

Overview of the growth coupled pathways towards this compound.

KEGG ID: C20435

Available chemistries

mth1

R + amet_c → R-methylated + ahcys_c

Methyltransferases

Reaction routes

3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcenemth1

2 S-Adenosyl-L-methionine + C30 Botryococcene ⇄ 2 S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

C30 Botryococcene

Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c

Reversibility:
-2.86±1.48

Presqualene diphosphate

Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c

Reversibility:
4.80±1.25

Squalene

2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c

Reversibility:
-21.77±0.55

3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcenemth1

S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene ⇄ S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene

S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

C30 Botryococcene

Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c

Reversibility:
-2.86±1.48

Presqualene diphosphate

Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c

Reversibility:
4.80±1.25

Squalene

2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c

Reversibility:
-21.77±0.55

3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcenemth1

S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene ⇄ S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene

S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c

Reversibility:
?

C30 Botryococcene

Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c

Reversibility:
-2.86±1.48

Presqualene diphosphate

Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c

Reversibility:
4.80±1.25

Squalene

2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c

Reversibility:
-21.77±0.55