Vanillate

3,4-Dihydroxybenzoate + 5-Methyltetrahydrofolate ⇄ Vanillate + Tetrahydrofolate (2.1.1.341)
5-Methyltetrahydrofolate: 5mthf_c

3,4-Dihydroxybenzoate

3-Carboxy-cis,cis-muconate ⇄ 3,4-Dihydroxybenzoate + O₂ (1.13.11.3)

Reversibility:

81.92±1.56

3-Carboxy-cis,cis-muconate

2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate ⇄ 3-Carboxy-cis,cis-muconate (5.5.1.2)

Reversibility:

-7.00±1.45

2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate

2-Oxo-2,3-dihydrofuran-5-acetate + CO₂ ⇄ 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate (4.1.1.44)
CO₂: co2_c

Reversibility:

16.23±1.49

2-Oxo-2,3-dihydrofuran-5-acetate

3-Oxoadipate ⇄ 2-Oxo-2,3-dihydrofuran-5-acetate + H₂O (3.1.1.24)

Reversibility:

9.95±1.63

3-Oxoadipate

Succinate + 3-Oxoadipyl-CoA ⇄ Succinyl-CoA + 3-Oxoadipate (2.8.3.6)
Succinate: succ_c, 3-Oxoadipyl-CoA: oxadpcoa_c

Reversibility:

0.69±0.33